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miR‐18a activates Wnt pathway in ER‐positive breast cancer and is associated with poor prognosis

16 Jun 2020

Abstract excerpt

Despite the established benefits of long-term endocrine therapy, women with hormone receptor-positive breast cancer remain at risk for late relapse. The basis of this is multi-factorial including genetic, epigenetic, and host factors. In this study we have explored the epigenetic regulation of estrogen receptor (ER)-dependent molecular and cellular phenotype by hsa-miR-18a-5p using well-established human...

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PMID: 32543775
DOI: 10.1002/cam4.3183

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