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Article

Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial.

BMC medical genetics - 24 Mar 2015

Thomas Sushma S, Makar Karen W, Li Lin, Zheng Yingye, Yang Peiying, Levy Lisa, Rudolph Rebecca Yvonne, Lampe Paul D, Yan Min, Markowitz Sanford D, Bigler Jeannette, Lampe Johanna W, Potter John D

Abstract excerpt

BACKGROUND: Regular aspirin use reduces colon adenoma and carcinoma incidence. UDP-glucuronosyltransferases (UGT) are involved in aspirin metabolism and clearance, and variant alleles in UGT1A6 have been shown to alter salicylic acid metabolism and risk of colon neoplasia. METHODS: In a randomize...

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Identifiers

PMID: 25927723
DOI: 10.1186/s12881-015-0161-6
PMCID: PMC4422425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25927723-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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