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Functional Genetic Variants in SPHK1 Affect Susceptibility to Gastric Cancer in a Chinese Population.

Clinical laboratory - 1 Sept 2017

Huan Xiangkun, He Yu, Huang Chi, Wang Younan, Zhu Yi, Xu Zekuan, Yang Li, Cao Huaxiang

Abstract excerpt

BACKGROUND: An escalating number of studies have provided identified evidence that sphingosine kinase 1 (SPHK1) plays an essential role in carcinogenesis. This present study was devised to seek the possible correlation of two tag single-nucleotide polymorphisms (SNPs) in SPHK1 (rs3744037 T>C, rs346801 C>T) with the susceptibility to gastric cancer (GC). METHODS: This present case-control study was comprised of...

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Identifiers

PMID: 28879695
DOI: 10.7754/Clin.Lab.2017.170212

Genes

SPHK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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