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Article

Association of SYK genetic variations with breast cancer pathogenesis.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Shakeel Shafaq, Mahjabeen Ishrat, Kayani Mahmood Akhtar, Faryal Rani

Abstract excerpt

Spleen tyrosine kinase (SYK) is a non-receptor type cytoplasmic protein and a known tumor suppressor gene in breast cancer. Polymorphisms in SYK have been reported to be associated with cell invasion/cell morality and an increased risk of cancer development. In this case control study, all exons of the SYK gene and its exon/ intron boundaries were amplified in 200 breast cancer cases and 100 matched controls and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23803121
DOI: 10.7314/apjcp.2013.14.5.3309

Genes

SYK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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