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Article

Thymidylate Synthase Polymorphisms and Risk of Lung Cancer among the Jordanian Population: a Case Control Study.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Qasem Wiam Al, Yousef Al-Motassem, Yousef Mohammad, Manasreh Ihab

Abstract excerpt

BACKGROUND: Thymidylate synthase (TS) catalyzes the methylation of deoxyuridylate to deoxythymidylate and is involved in DNA methylation, synthesis and repair. Two common polymorphisms have been reported, tandem repeats in the promoter-enhancer region (TSER), and 6bp ins/del in the 5'UTR, that are implicated in a number of human diseases, including cancer. The association between the two polymorphisms in risk for...

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Identifiers

PMID: 26745074
DOI: 10.7314/apjcp.2015.16.18.8287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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