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Article

Relationship between Genetic Polymorphisms in MTHFR (C677T, A1298C and their Haplotypes) and the Incidence Of Breast Cancer among Jordanian Females--Case-Control Study.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Awwad Nemah, Yousef Al-Motassem, Abuhaliema Ali, Abdalla Ihab, Yousef Muhammad

Abstract excerpt

BACKGROUND: Breast cancer is a major cause of morbidity and mortality in Jordan and worldwide. Abnormality of DNA methylation is a possible mechanism for the development of cancer. Methylenetetrahydrofolate reductase (MTHFR) is involved in DNA methylation. Our aim was to study the association between genetic polymorphisms of MTHFR at two sites (C677T and A1298C) and their haplotypes and the risk of breast cancer...

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Identifiers

PMID: 26163632
DOI: 10.7314/apjcp.2015.16.12.5007

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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