Article
Genetic predisposition to papillary thyroid carcinoma is mediated by a long non-coding RNA TINCR enhancer polymorphism.
International immunopharmacology - 1 Aug 2022
Wang Qiang, Huang Hong, Chen Peng, Xiao Xiao, Luo Xiaolei, Wang Yanyun, Long Siyu, Gao Linbo, Zhang Lin
Abstract excerpt
Single nucleotide polymorphisms (SNPs) in the enhancer region have been demonstrated to confer to altered enhancer activities, aberrant gene expression, and cancer susceptibility. In this study, we aimed to examine the association between an SNP, rs8101923, within terminal differentiation-induced non-coding RNA (TINCR) and the risk of papillary thyroid carcinoma (PTC). Blood samples from 559 patients with PTC and...
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