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Article

Response to potent anti-HBV agents in chronic hepatitis B and combined effect of HBV reverse transcriptase mutations.

Gene - 1 Aug 2015

Singla Bhupesh, Bhattacharyya Rajasri, Chakraborti Anuradha, Sharma Bal Krishan, Kapil Shweta, Chawla Yogesh K, Arora Sunil K, Das Ashim, Dhiman Radha K, Duseja Ajay

Abstract excerpt

BACKGROUND AND AIM: Response to nucleos(t)ide analogue therapy against HBV infection depends on a number of factors. One of them is appearance of drug resistance mutations. The present study aimed to investigate the efficacy of ETV and TDF as anti-HBV agents and to analyze the role of HBV-RT mutations in reducing the efficacy of mentioned drugs. MATERIAL AND METHODS: Sixty nine treatment naïve CHB patients (mean...

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Identifiers

PMID: 25917965
DOI: 10.1016/j.gene.2015.04.060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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