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Article

Presynaptic BK channel localization is dependent on the hierarchical organization of alpha-catulin and dystrobrevin and fine-tuned by CaV2 calcium channels.

BMC neuroscience - 24 Apr 2015

Oh Kelly H, Abraham Linu S, Gegg Chandler, Silvestri Christian, Huang Yung-Chi, Alkema Mark J, Furst Jacob, Raicu Daniela, Kim Hongkyun

Abstract excerpt

BACKGROUND: Large conductance, calcium-activated BK channels regulate many important physiological processes, including smooth muscle excitation, hormone release and synaptic transmission. The biological roles of these channels hinge on their unique ability to respond synergistically to both voltage and cytosolic calcium elevations. Because calcium influx is meticulously regulated both spatially and temporally,...

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Identifiers

PMID: 25907097
DOI: 10.1186/s12868-015-0166-2
PMCID: PMC4411755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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