Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression and mutations of KCNJ5 mRNA in Japanese patients with aldosterone-producing adenomas.

The Journal of clinical endocrinology and metabolism - 1 Apr 2012

Taguchi Ryo, Yamada Masanobu, Nakajima Yasuyo, Satoh Tetsurou, Hashimoto Koshi, Shibusawa Nobuyuki, Ozawa Atsushi, Okada Shuichi, Rokutanda Nana, Takata Daisuke, Koibuchi Yukio, Horiguchi Jun, Oyama Tetsunari, Takeyoshi Izumi, Mori Masatomo

Abstract excerpt

CONTEXT: Mutations of the KCNJ5 gene have recently been identified in patients with aldosterone-producing adenomas (APA). OBJECTIVE: Our objective was to investigate the expression and mutations of the KCNJ5 gene in Japanese patients with APA. DESIGN AND PATIENTS: We sequenced KCNJ5 cDNA and measured KCNJ5 mRNA levels in 23 patients with APA operated on at Gunma University Hospital. MAIN OUTCOME MEASURES:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal Cortex Neoplasms
Share to Adrenal Gland Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Adrenocortical Adenoma

Share to Cushing Syndrome

Share to G Protein-Coupled Inwardly-Rectifying Potassium Channels

Share to Hyperaldosteronism

Share to Neoplasm Proteins

Share to Pheochromocytoma

Source

Identifiers

PMID: 22278422
DOI: 10.1210/jc.2011-2885

Genes

KCNJ5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression and mutations of KCNJ5 mRNA in Japanese patients with aldosterone-producing adenomas.PMID 22278422Read ↗

Characteristics of Japanese aldosterone-producing adenomas with KCNJ5 mutations.Semantic proximity Read ↗

Prevalence and characterization of somatic mutations in Chinese aldosterone-producing adenoma patients.Semantic proximity Read ↗

Genetics of Aldosterone-Producing Adenoma in Korean Patients.Semantic proximity Read ↗

Effect of KCNJ5 mutations on gene expression in aldosterone-producing adenomas and adrenocortical cells.Semantic proximity Read ↗

Clinical characteristics of somatic mutations in Chinese patients with aldosterone-producing adenoma.Semantic proximity Read ↗

Prevalence of Somatic Mutations in Aldosterone-Producing Adenomas in Japanese Patients.Semantic proximity Read ↗

Comparison of cardiovascular complications in patients with and without KCNJ5 gene mutations harboring aldosterone-producing adenomas.Semantic proximity Read ↗

[Research progress of KCNJ5 gene in aldosterone-producing adenoma].Semantic proximity Read ↗

A Meta-Analysis of Somatic KCNJ5 K(+) Channel Mutations In 1636 Patients With an Aldosterone-Producing Adenoma.Semantic proximity Read ↗

Prevalence, clinical, and molecular correlates of KCNJ5 mutations in primary aldosteronism.Semantic proximity Read ↗

Comprehensive re-sequencing of adrenal aldosterone producing lesions reveal three somatic mutations near the KCNJ5 potassium channel selectivity filter.Semantic proximity Read ↗

Prevalence of Somatic KCNJ5 Mutations in Thai Patients With Aldosterone-Producing Adrenal AdenomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.