Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic diversity of the Pneumococcal CbpA: Implications for next-generation vaccine development.

Human vaccines & immunotherapeutics - 1 Jan 2015

Abry Muna F, Kimenyi Kelvin M, Osowo Fred O, Odhiambo Willingtone O, Sewe Steven O, Kulohoma Benard W

Abstract excerpt

Pneumococci are capable of vaccine escape by genetic recombination at the targeted capsular locus, significantly reducing long-term vaccine effectiveness. Recently, efforts have been redirected to understanding pneumococcal biology related to potential next-generation vaccine candidates. A variety of serotype-independent protein antigens capable of inducing protective immune responses in tissue culture and animal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Bacterial
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conserved Sequence

Share to Drug Discovery

Share to Epitopes

Share to Pneumococcal Vaccines

Share to Protein Conformation

Share to Protein Structure, Tertiary

Source

Open in PubMed Open full text

Identifiers

PMID: 25902300
DOI: 10.1080/21645515.2015.1021521
PMCID: PMC4514174

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic diversity of the Pneumococcal CbpA: Implications for next-generation vaccine development.PMID 25902300Read ↗

Genetic diversity of pneumococcal surface protein A in invasive pneumococcal isolates from Korean children, 1991-2016.Semantic proximity Read ↗

Global genomic pathogen surveillance to inform vaccine strategies: a decade-long expedition in pneumococcal genomicsSemantic proximity Read ↗

The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1.Semantic proximity Read ↗

Putatively novel serotypes and the potential for reduced vaccine effectiveness: capsular locus diversity revealed among 5405 pneumococcal genomes.Semantic proximity Read ↗

Pneumococcal Surface Proteins as Virulence Factors, Immunogens, and Conserved Vaccine TargetsSemantic proximity Read ↗

Bacterial genome variability and its impact on vaccine design.Semantic proximity Read ↗

Use of a Whole Genome Approach To Identify Vaccine Molecules Affording Protection against Streptococcus pneumoniae InfectionSemantic proximity Read ↗

Monitoring the long-term molecular epidemiology of the pneumococcus and detection of potential 'vaccine escape' strains.Semantic proximity Read ↗

New pneumococcal serotype 20C is a WciG O-acetyltransferase deficient variant of canonical serotype 20BSemantic proximity Read ↗

Differences among group A streptococcus epidemiological landscapes: consequences for M protein-based vaccines?Semantic proximity Read ↗

Pneumococcal genetic variability influences age-dependent bacterial carriageSemantic proximity Read ↗

Global population structure and phase variation of serotype 12F <i>Streptococcus pneumoniae</i> following the introduction of pneumococcal conjugate vaccineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.