Article
Interleukin 1 beta (IL-1β) promoter C [-511] T polymorphism but not C [+3953] T polymorphism is associated with polycystic ovary syndrome.
Endocrine - 1 Feb 2010
Mu Yuan, Liu Jingjing, Wang Binbin, Wen Qiaolian, Wang Jing, Yan Jinting, Zhou Sirui, Ma Xu, Cao Yunxia
Abstract excerpt
PCOS is a complex multifactorial disorder involving a number of genetic and environmental factors. One of the genetic factors that has been associated with PCOS is Interleukin 1 beta (IL-1β), is an important inflammatory cytokine that plays a regulatory role in both the body's immune and the inflammatory responses. All these responses appear to be are also affected in at least some women with PCOS. To investigate...
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