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Article

Differential Lipid Response to Statins Is Associated With Variants in the BUD13-APOA5 Gene Region.

Journal of cardiovascular pharmacology - 1 Aug 2015

OʼBrien Sarah E, Schrodi Steven J, Ye Zhan, Brilliant Murray H, Virani Salim S, Brautbar Ariel

Abstract excerpt

Genetic variants within the BUD13-APOA5 gene region are known to be associated with high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG) levels. Recent studies suggest that single nucleotide polymorphisms (SNPs) within this region affect HDL-C response to statin-fibrate combination therapy and low-density lipoprotein cholesterol (LDL-C) response to statin therapy. We hypothesized that SNPs within...

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Source

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Identifiers

PMID: 25900265
DOI: 10.1097/FJC.0000000000000261
PMCID: PMC4993018

Genes

APOA5
BUD13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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