Article
Effects of Polymorphisms in APOA4-APOA5-ZNF259-BUD13 Gene Cluster on Plasma Levels of Triglycerides and Risk of Coronary Heart Disease in a Chinese Han Population.
PloS one - 1 Jan 2015
Fu Qianxi, Tang Xiaojun, Chen Juan, Su Li, Zhang Mingjun, Wang Long, Jing Jinjin, Zhou Li
Abstract excerpt
BACKGROUND/AIM: Recent genome-wide association studies have identified several loci influencing lipid levels. The present study focused on the triglycerides (TG)-associated locus, the APOA4-APOA5-ZNF259-BUD13 gene cluster on chromosome 11, to explore the role of genetic variants in this gene cluster in the development of increasing TG levels and coronary heart disease (CHD). METHODOLOGY/PRINCIPAL FINDINGS: Six...
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