Article
Low-dose chemotherapy with methotrexate and vinblastine for patients with desmoid tumors: relationship to CTNNB1 mutation status.
International journal of clinical oncology - 1 Dec 2015
Nishida Yoshihiro, Tsukushi Satoshi, Urakawa Hiroshi, Hamada Shunsuke, Kozawa Eiji, Ikuta Kunihiro, Ando Yuichi, Ishiguro Naoki
Abstract excerpt
BACKGROUND: This study was conducted to determine the efficacy and safety of low-dose chemotherapy with methotrexate (MTX) and vinblastine (VBL) for patients with desmoid tumors refractory to meloxicam treatment, focusing in particular on the relationship between the efficacy of this chemotherapy and catenin β-1 (CTNNB1) mutation status. PATIENTS AND METHODS: Since March 2003, patients pathologically diagnosed...
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