Long-term Outcomes of Oral Vinorelbine in Advanced, Progressive Desmoid Fibromatosis and Influence of CTNNB1 Mutational Status.

doi:10.1158/1078-0432.CCR-20-1847

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Article

Long-term Outcomes of Oral Vinorelbine in Advanced, Progressive Desmoid Fibromatosis and Influence of CTNNB1 Mutational Status.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2020

Mir Olivier, Honoré Charles, Chamseddine Ali N, Dômont Julien, Dumont Sarah N, Cavalcanti Andrea, Faron Matthieu, Rimareix Françoise, Haddag-Miliani Leila, Le Péchoux Cécile, Levy Antonin, Court Charles, Briand Sylvain, Fadel Elie, Mercier Olaf, Bayle Arnaud, Brunet Anaïs, Ngo Carine, Rouleau Etienne, Adam Julien, Le Cesne Axel

Abstract excerpt

PURPOSE: Desmoid-type fibromatosis (DF) are locally aggressive neoplasms, with a need for effective systemic treatment in case of progression to avoid the short- and long-term complications of local treatments. EXPERIMENTAL DESIGN: We retrospectively analyzed the outcomes of adult patients with DF treated with oral vinorelbine (90 mg once weekly) at Gustave Roussy Cancer Institute (Villejuif, Paris, France). Only...

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PMID: 32873570
DOI: 10.1158/1078-0432.CCR-20-1847

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