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Article

Characteristics of cultured desmoid cells with different CTNNB1 mutation status.

Cancer medicine - 1 Feb 2016

Hamada Shunsuke, Urakawa Hiroshi, Kozawa Eiji, Arai Eisuke, Ikuta Kunihiro, Sakai Tomohisa, Ishiguro Naoki, Nishida Yoshihiro

Abstract excerpt

Desmoid tumors are benign mesenchymal neoplasms with a locally aggressive nature. The mutational status of β-catenin gene (CTNNB1) is presumed to affect the tumorous activity of the cells. In this study, we isolated three kinds of desmoid cell with different CTNNB1 status, and compared their characteristics. Cells were isolated from three patients with abdominal wall desmoid during surgery, all of which were...

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Source

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Identifiers

PMID: 26686699
DOI: 10.1002/cam4.582
PMCID: PMC4735788

Genes

CTNNB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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