Article
Immunohistochemical staining with non-phospho β-catenin as a diagnostic and prognostic tool of COX-2 inhibitor therapy for patients with extra-peritoneal desmoid-type fibromatosis.
Diagnostic pathology - 29 Aug 2017
Sakai Tomohisa, Nishida Yoshihiro, Hamada Shunsuke, Koike Hiroshi, Ikuta Kunihiro, Ota Takehiro, Ishiguro Naoki
Abstract excerpt
BACKGROUND: Immunohistochemical staining with conventional anti-β-catenin antibody has been applied as a diagnostic tool for desmoid-type fibromatosis (DF). This study aimed to evaluate the diagnostic and prognostic value of immunohistochemical staining with anti-non-phospho β-catenin antibody, which might more accurately reflect the aggressiveness of DF, in comparison to the conventional anti-β-catenin antibody....
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