Article
Truncated products of the vestigial proliferation gene induce apoptosis.
Cell death and differentiation - 1 Jun 1999
Van de Bor V, Delanoue R, Cossard R, Silber J
Abstract excerpt
The vestigial (vg) gene in D. melanogaster, whose mutant phenotype is characterized by wing atrophy, encodes a novel nuclear protein involved in cell proliferation. The original vg mutant (vgBG) displays massive apoptosis in the wing imaginal disc. Here we tested the hypothesis that the vg mutant phenotype could be due: (i) to lack of cell proliferation in null mutants due to the absence of the Vg product and,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.