A comprehensive meta-analysis of association between genetic variants of GDF5 and osteoarthritis of the knee, hip and hand.

doi:10.1007/s00011-015-0818-9

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Article

A comprehensive meta-analysis of association between genetic variants of GDF5 and osteoarthritis of the knee, hip and hand.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] - 1 Jun 2015

Zhang Rui, Yao Jianfeng, Xu Peng, Ji Baohu, Luck James V, Chin Brian, Lu Shemin, Kelsoe John R, Ma Jie

Abstract excerpt

OBJECTIVE: A number of studies have reported an association of GDF5 with osteoarthritis (OA) but have produced some divergent findings and their interpretation may not be straightforward. METHODS: We investigated the association between GDF5 and OA using meta-analytic techniques, combining all published data up to Nov 2014. 16 independent samples from 11 research teams contributed data on SNP rs143383 (located in...

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PMID: 25894512
DOI: 10.1007/s00011-015-0818-9

Genes

GDF5

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