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Article

MKAN27435 is required for the biosynthesis of higher subclasses of lipooligosaccharides in Mycobacterium kansasii.

PloS one - 1 Jan 2015

Nataraj Vijayashankar, Pang Poh-choo, Haslam Stuart M, Veerapen Natacha, Minnikin David E, Dell Anne, Besra Gurdyal S, Bhatt Apoorva

Abstract excerpt

Lipooligosaccharides are glycolipids found in the cell wall of many mycobacterial species including the opportunistic pathogen Mycobacterium kansasii. The genome of M. kansasii ATCC12478 contains a cluster with genes orthologous to Mycobacterium marinum LOS biosynthesis genes. To initiate a genetic dissection of this cluster and demonstrate its role in LOS biosynthesis in M. kansasii, we chose MKAN27435, a gene...

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PMID: 25893968
DOI: 10.1371/journal.pone.0122804
PMCID: PMC4403928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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