Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A second endolysin gene is fully embedded in-frame with the lysA gene of mycobacteriophage Ms6.

PloS one - 1 Jan 2011

Catalão Maria João, Milho Catarina, Gil Filipa, Moniz-Pereira José, Pimentel Madalena

Abstract excerpt

Mycobacteriophages are dsDNA viruses that infect mycobacterial hosts. The mycobacteriophage Ms6 accomplishes lysis by producing two cell wall hydrolytic enzymes, Lysin A (LysA) that possesses a central peptidoglycan recognition protein (PGRP) super-family conserved domain with the amidase catalytic site, that cleaves the amide bond between the N-acetylmuramic acid and L-alanine residues in the oligopeptide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriolysis
Share to Cell Wall
Share to Endopeptidases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Viral

Share to Hydrolysis

Share to Mycobacterium smegmatis

Share to N-Acetylmuramoyl-L-alanine Amidase

Share to Viral Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21694774
DOI: 10.1371/journal.pone.0020515
PMCID: PMC3111421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A second endolysin gene is fully embedded in-frame with the lysA gene of mycobacteriophage Ms6.PMID 21694774Read ↗

Analysis of a Novel Cluster V Mycobacteriophage EniyanLRS and its Therapeutically Relevant LysBSemantic proximity Read ↗

Molecular Aspects and Comparative Genomics of Bacteriophage EndolysinsSemantic proximity Read ↗

MTB-LysB1:A Novel Endolysin Against Multidrug-Resistant <i>Mycobacterium tuberculosis</i>Semantic proximity Read ↗

The Phage Lytic Proteins from the Staphylococcus aureus Bacteriophage vB_SauS-phiIPLA88 Display Multiple Active Catalytic Domains and Do Not Trigger Staphylococcal ResistanceSemantic proximity Read ↗

Functional Characterization of the N-Acetylmuramyl-l-Alanine Amidase, Ami1, from Mycobacterium abscessus.Semantic proximity Read ↗

Disruption of msl3 abolishes the synthesis of mycolipanoic and mycolipenic acids required for polyacyltrehalose synthesis in Mycobacterium tuberculosis H37Rv and causes cell aggregation.Semantic proximity Read ↗

Mycobacteriophage Marvin: a New Singleton Phage with an Unusual Genome OrganizationSemantic proximity Read ↗

CpsA, a LytR-CpsA-Psr Family Protein in Mycobacterium marinum, Is Required for Cell Wall Integrity and VirulenceSemantic proximity Read ↗

A novel type of peptidoglycan-binding domain highly specific for amidated D-Asp cross-bridge, identified in Lactobacillus casei bacteriophage endolysins.Semantic proximity Read ↗

Therapeutically useful mycobacteriophages BPs and Muddy require trehalose polyphleatesSemantic proximity Read ↗

Fusion with a cell wall binding domain renders autolysin LytM a potent anti-Staphylococcus aureus agentSemantic proximity Read ↗

Deciphering the Role of Holin in Mycobacteriophage D29 PhysiologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.