Article
The Biosynthesis of Lipooligosaccharide from Bacteroides thetaiotaomicron.
mBio - 13 Mar 2018
Jacobson Amy N, Choudhury Biswa P, Fischbach Michael A
Abstract excerpt
Lipopolysaccharide (LPS), a cell-associated glycolipid that makes up the outer leaflet of the outer membrane of Gram-negative bacteria, is a canonical mediator of microbe-host interactions. The most prevalent Gram-negative gut bacterial taxon, Bacteroides, makes up around 50% of the cells in a typical Western gut; these cells harbor ~300 mg of LPS, making it one of the highest-abundance molecules in the...
Topics
- Bacteroides thetaiotaomicron
- Biosynthetic Pathways
- Lipopolysaccharides
- Mutation
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization