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Article

Associations of PER3 and RORA Circadian Gene Polymorphisms and Depressive Symptoms in Older Adults.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Oct 2015

Maglione Jeanne E, Nievergelt Caroline M, Parimi Neeta, Evans Daniel S, Ancoli-Israel Sonia, Stone Katie L, Yaffe Kristine, Redline Susan, Tranah Gregory J

Abstract excerpt

BACKGROUND: Depressive symptoms are common in older adults and associated with poor outcomes. Although circadian genes have been implicated in depression, the relationship between circadian genes and depressive symptoms in older adults is unclear. METHODS: A cross-sectional genetic association study of 529 single nucleotide polymorphisms (SNPs) representing 30 candidate circadian genes was performed in two...

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Identifiers

PMID: 25892098
DOI: 10.1016/j.jagp.2015.03.002
PMCID: PMC4568170

Genes

PER3
RORA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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