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Article

The effect of rare alleles on estimated genomic relationships from whole genome sequence data.

BMC genetics - 12 Mar 2015

Eynard Sonia E, Windig Jack J, Leroy Grégoire, van Binsbergen Rianne, Calus Mario P L

Abstract excerpt

BACKGROUND: Relationships between individuals and inbreeding coefficients are commonly used for breeding decisions, but may be affected by the type of data used for their estimation. The proportion of variants with low Minor Allele Frequency (MAF) is larger in whole genome sequence (WGS) data compared to Single Nucleotide Polymorphism (SNP) chips. Therefore, WGS data provide true relationships between individuals...

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PMID: 25887220
DOI: 10.1186/s12863-015-0185-0
PMCID: PMC4365517

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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