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Article

Whole-genome sequence data uncover loss of genetic diversity due to selection.

Genetics, selection, evolution : GSE - 14 Apr 2016

Eynard Sonia E, Windig Jack J, Hiemstra Sipke J, Calus Mario P L

Abstract excerpt

BACKGROUND: Whole-genome sequence (WGS) data give access to more complete structural genetic information of individuals, including rare variants, not fully covered by single nucleotide polymorphism chips. We used WGS to investigate the amount of genetic diversity remaining after selection using optimal contribution (OC), considering different methods to estimate the relationships used in OC. OC was applied to...

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Identifiers

PMID: 27080121
DOI: 10.1186/s12711-016-0210-4
PMCID: PMC4831198

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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