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Article

Gene polymorphisms in RANKL/RANK/OPG pathway are associated with ages at menarche and natural menopause in Chinese women.

BMC women's health - 13 Apr 2015

Duan Peng, Wang Zhi-Ming, Liu Jiang, Wang Li-Na, Yang Zhi, Tu Ping

Abstract excerpt

BACKGROUND: Age at menarche (AAM) and age at natural menopause (AANM) have been shown intimately associated with woman's health later in life. Previous studies have indicated that AAM and AANM are highly heritable. RANKL/RANK/OPG signaling pathway is essential for mammary gland development, which is also found associated with post-menopausal and hormone-related diseases. The aim of this study was to evaluate...

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Source

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Identifiers

PMID: 25884698
DOI: 10.1186/s12905-015-0192-3
PMCID: PMC4397679

Genes

TNFSF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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