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Article

Near-atomic cryo-EM structure of the helical measles virus nucleocapsid

17 Apr 2015

Abstract excerpt

Measles is a highly contagious human disease. We used cryo-electron microscopy and single particle-based helical image analysis to determine the structure of the helical nucleocapsid formed by the folded domain of the measles virus nucleoprotein encapsidating an RNA at a resolution of 4.3 angstroms. The resulting pseudoatomic model of the measles virus nucleocapsid offers important insights into the mechanism of...

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PMID: 25883315
DOI: 10.1126/science.aaa5137

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