Article
Paramyxovirus Ultrastructure and Genome Packaging: Cryo-Electron Tomography of Sendai Virus
4 Jun 2009
Abstract excerpt
Members of the Paramyxoviridae such as measles, mumps, and parainfluenza viruses have pleomorphic, enveloped virions that contain negative-sense unsegmented RNA genomes. This is encapsidated by multiple copies of a viral nucleocapsid protein N to form a helical ribonucleoprotein complex (termed the nucleocapsid), which acts as the template for both transcription and replication. Structure analysis of these...
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