Genotype screening of APLN rs3115757 variant in Egyptian women population reveals an association with obesity and insulin resistance.

doi:10.1016/j.diabres.2015.05.016

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Article

Genotype screening of APLN rs3115757 variant in Egyptian women population reveals an association with obesity and insulin resistance.

Diabetes research and clinical practice - 1 Jul 2015

Aboouf Mostafa A, Hamdy Nadia M, Amin Ashraf I, El-Mesallamy Hala O

Abstract excerpt

AIMS: Apelin is one of adipokines that plays a pivotal role in energy metabolism, insulin sensitivity and vascular integrity. A definite genetic variant of apelin gene (APLN), rs3115757, was recently introduced to potentially influence apelin expression in adipocytes. The aim of our study was to explore the sights of a potential association of this functional variant with obesity traits, insulin resistance...

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PMID: 26025696
DOI: 10.1016/j.diabres.2015.05.016

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APLN

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