Article
Target Acquired: Progress and Promise of Targeted Therapeutics in the Treatment of Prostate Cancer.
Current cancer drug targets - 1 Jan 2015
Stuchbery Ryan, Kurganovs Natalie J, McCoy Patrick J, Nelson Colleen C, Hayes Vanessa M, Corcoran Niall M, Hovens Christopher M
Abstract excerpt
Cancer is fundamentally a genomic disease caused by mutations or rearrangements in the DNA or epigenetic machinery of a patient. An emerging field in cancer treatment targets key aberrations arising from the mutational landscape of an individual patient's disease rather than employing a cancer-wide cytotoxic therapy approach. In prostate cancer in particular, where there is an observed variation in response to...
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