Molecular Alterations in Prostate Cancer as Diagnostic, Prognostic, and Therapeutic Targets

Abstract excerpt

Prostatic adenocarcinoma is extremely common in Western nations, representing the second leading cause of cancer death in American men. The recent application of increasingly sophisticated molecular approaches to the study of prostate cancer in this "postgenomic" era has resulted in a rapid increase in the identification of somatic genome alterations and germline heritable risk factors in this disease. These...

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