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Article

Association between genetic polymorphisms and carotid atherosclerosis in patients treated with radiotherapy for nasopharyngeal carcinoma.

Radiation oncology (London, England) - 13 Feb 2015

Yuan Chuang, Yip Shea Ping, Wu Vincent W C, Kwong Dora L W, Cheuk Isabella W Y, Ying Michael

Abstract excerpt

BACKGROUND: Radiotherapy (RT) of the neck is commonly given to nasopharyngeal carcinoma (NPC) patients for preventing cervical lymph node metastasis. However, neck RT may induce the development of carotid atherosclerosis. The mechanisms of radiation-induced carotid atherosclerosis are still unclear and no previous study has investigated the genetic involvement of radiation-induced carotid atherosclerosis. The...

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Identifiers

PMID: 25880731
DOI: 10.1186/s13014-015-0341-8
PMCID: PMC4332433

Genes

PON1
ADIPOQ
CAT
NOS3
PPARG
SOD2
SOD3
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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