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Article

A genetic variant in the promoter of phosphate-activated glutaminase is associated with hepatic encephalopathy.

Journal of internal medicine - 1 Sept 2015

Mayer L B, Krawczyk M, Grünhage F, Lammert F, Stokes C S

Abstract excerpt

BACKGROUND: Hepatic encephalopathy (HE) is a serious complication of liver cirrhosis. Recently, a microsatellite in the promoter region of the phosphate-activated glutaminase (GLS ) gene was associated with the risk of HE. The aim of the present study was to investigate, using the critical flicker frequency (CFF) test, whether the described GLS variant increases the risk of developing HE in patients with...

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Source

Identifiers

PMID: 25880019
DOI: 10.1111/joim.12374

Genes

GLS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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