Article
Validation study associating glutaminase promoter variations with hepatic encephalopathy in East Asian populations.
Journal of gastroenterology and hepatology - 1 Apr 2017
Ahn Jem Ma, Kim Chang Ha, Um Soon Ho, Kim Kyung Mee, Kim Tae Hyung, Yim Sun Young, Choi Hyuk Soon, Kim Eun Sun, Keum Bora, Seo Yeon Seok, Yim Hyung Joon, Jeen Yoon Tae, Lee Hong Sik, Chun Hoon Jai, Kim Chang Duck, Ryu Ho Sang
Abstract excerpt
BACKGROUND AND AIM: In a recent study, microsatellite variations (GCA tandem repeats) in the promoter region of the (kidney-type) glutaminase gene were associated with the development of hepatic encephalopathy (HE) in Spanish patients with cirrhosis. The objective of this study was to validate the relation between microsatellite variations in the glutaminase promoter region and the development of overt HE in...
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