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Article

Role of polymorphisms of inducible nitric oxide synthase and endothelial nitric oxide synthase in idiopathic environmental intolerances.

Mediators of inflammation - 1 Jan 2015

De Luca Chiara, Gugliandolo Agnese, Calabrò Carlo, Currò Monica, Ientile Riccardo, Raskovic Desanka, Korkina Ludmila, Caccamo Daniela

Abstract excerpt

Oxidative stress and inflammation play a pathogenetic role in idiopathic environmental intolerances (IEI), namely, multiple chemical sensitivity (MCS), fibromyalgia (FM), and chronic fatigue syndrome (CFS). Given the reported association of nitric oxide synthase (NOS) gene polymorphisms with inflammatory disorders, we aimed to investigate the distribution of NOS2A -2.5 kb (CCTTT) n as well as Ser608Leu and NOS3...

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Identifiers

PMID: 25878398
DOI: 10.1155/2015/245308
PMCID: PMC4387900

Genes

NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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