Article
Dynamic determination of the functional state in photolyase and the implication for cryptochrome.
Proceedings of the National Academy of Sciences of the United States of America - 6 Aug 2013
Liu Zheyun, Zhang Meng, Guo Xunmin, Tan Chuang, Li Jiang, Wang Lijuan, Sancar Aziz, Zhong Dongping
Abstract excerpt
The flavin adenine dinucleotide cofactor has an unusual bent configuration in photolyase and cryptochrome, and such a folded structure may have a functional role in initial photochemistry. Using femtosecond spectroscopy, we report here our systematic characterization of cyclic intramolecular electron transfer (ET) dynamics between the flavin and adenine moieties of flavin adenine dinucleotide in four redox forms...
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