Article
Dynamics and mechanism of dimer dissociation of photoreceptor UVR8.
Nature communications - 10 Jan 2022
Li Xiankun, Liu Zheyun, Ren Haisheng, Kundu Mainak, Zhong Frank W, Wang Lijuan, Gao Jiali, Zhong Dongping
Abstract excerpt
Photoreceptors are a class of light-sensing proteins with critical biological functions. UVR8 is the only identified UV photoreceptor in plants and its dimer dissociation upon UV sensing activates UV-protective processes. However, the dissociation mechanism is still poorly understood. Here, by integrating extensive mutations, ultrafast spectroscopy, and computational calculations, we find that the funneled...
Topics
- Anions
- Arabidopsis
- Arabidopsis Proteins
- Arginine
- Binding Sites
- Chromosomal Proteins, Non-Histone
- Cloning, Molecular
- Escherichia coli
- Gene Expression
- Genetic Vectors
- Kinetics