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Article

Association of fatty-acid synthase polymorphisms and expression with outcomes after radical prostatectomy.

Prostate cancer and prostatic diseases - 1 Jun 2015

Cheng J, Ondracek R P, Mehedint D C, Kasza K A, Xu B, Gill S, Azabdaftari G, Yao S, Morrison C D, Mohler J L, Marshall J R

Abstract excerpt

BACKGROUND: Fatty-acid synthase (FASN), selectively overexpressed in prostate cancer (PCa) cells, has been described as linked to the aggressiveness of PCa. Constitutional genetic variation of the FASN gene and the expression levels of FASN protein in cancer cells could thus be expected to predict outcome after radical prostatectomy (RP). This study evaluates the associations of malignant tissue status,...

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Source

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Identifiers

PMID: 25868764
DOI: 10.1038/pcan.2015.11
PMCID: PMC4750391

Genes

FASN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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