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Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria

3 Nov 2009

Abstract excerpt

The assembly of vital reactive iron-sulfur (Fe-S) cofactors in eukaryotes is mediated by proteins inherited from the original mitochondrial endosymbiont. Uniquely among eukaryotes, however, Entamoeba and Mastigamoeba lack such mitochondrial-type Fe-S cluster assembly proteins and possess instead an analogous bacterial-type system acquired by lateral gene transfer. Here we demonstrate, using immunomicroscopy and...

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PMID: 19888992
DOI: 10.1111/j.1462-5822.2009.01397.x

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