Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

APOE polymorphisms contribute to reduced atorvastatin response in Chilean Amerindian subjects.

International journal of molecular sciences - 9 Apr 2015

Lagos Jenny, Zambrano Tomás, Rosales Alexy, Salazar Luis A

Abstract excerpt

Genetic factors can determine the high variability observed in response to lipid-lowering therapy with statins. Nonetheless, the frequency of single nucleotide polymorphisms (SNPs) and their impact can vary due to ethnicity. Because the Chilean population carries a strong Amerindian background, t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E
Share to Atorvastatin
Share to Chile

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Mitochondrial

Share to Haplotypes

Share to Hypercholesterolemia

Share to Polymorphism, Single Nucleotide

Share to Receptors, LDL

Source

Open in PubMed Open full text

Identifiers

PMID: 25860945
DOI: 10.3390/ijms16047890
PMCID: PMC4425056

Genes

APOE
LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25860945-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

APOE polymorphisms contribute to reduced atorvastatin response in Chilean Amerindian subjects.PMID 25860945Read ↗

Influence of SREBP-2 and SCAP gene polymorphisms on lipid-lowering response to atorvastatin in a cohort of Chilean subjects with Amerindian background.Semantic proximity Read ↗

SLCO1B1 c.388A>G Polymorphism Is Associated with HDL-C Levels in Response to Atorvastatin in Chilean Individuals.Semantic proximity Read ↗

Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia.Semantic proximity Read ↗

HMGCR rs17671591 SNP Determines Lower Plasma LDL-C after Atorvastatin Therapy in Chilean Individuals.Semantic proximity Read ↗

Genetic variation in key genes associated with statin therapy in the Azores Islands (Portugal) healthy population.Semantic proximity Read ↗

Gender-Specific Association Between ABCC2 -24C>T SNP and Reduction in Triglycerides in Chilean Patients Treated With Atorvastatin.Semantic proximity Read ↗

Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population.Semantic proximity Read ↗

Do MDR1 and SLCO1B1 polymorphisms influence the therapeutic response to atorvastatin? A study on a cohort of Egyptian patients with hypercholesterolemia.Semantic proximity Read ↗

Pharmacogenetics of Apolipoprotein E Gene During Lipid-Lowering Therapy: Lipid Levels and Prevention of Coronary Heart DiseaseSemantic proximity Read ↗

PON1 polymorphisms are predictors of ability to attain HDL-C goals in statin-treated patients.Semantic proximity Read ↗

Influence of SLCO1B1 polymorphisms on atorvastatin efficacy and safety in Macedonian subjects.Semantic proximity Read ↗

The Association between Apolipoprotein E Polymorphism and Response to Statins in Group of Hyperlipidemic Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.