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Article

Influence of SREBP-2 and SCAP gene polymorphisms on lipid-lowering response to atorvastatin in a cohort of Chilean subjects with Amerindian background.

Molecular diagnosis & therapy - 1 Aug 2014

Lagos Jenny, Zambrano Tomás, Rosales Alexy, Salazar Luis A

Abstract excerpt

BACKGROUND AND OBJECTIVES: This study evaluated the influence of the polymorphisms G1784C (rs4822063) and A2386G (rs12487736) of SREBP-2 and SCAP genes, respectively, on the response to atorvastatin treatment in a cohort of Chilean subjects with Amerindian background. METHODS: A total of 142 hypercholesterolemic individuals underwent atorvastatin therapy (10 mg/day/1 month). Serum lipids levels before and after...

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Source

Identifiers

PMID: 24615250
DOI: 10.1007/s40291-014-0094-3

Genes

SCAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Influence of SREBP-2 and SCAP gene polymorphisms on lipid-lowering response to atorvastatin in a cohort of Chilean subjects with Amerindian background.PMID 24615250Read ↗

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