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Article

Characterization of Circulating Tumor DNA for Genetic Assessment of solid Tumors.

Clinical pharmacology and therapeutics - 1 Jul 2015

Dorner A J, Badola S, Niu H

Abstract excerpt

Personalized cancer therapy requires characterization of the current status of an individual's cancer, necessitating invasive tumor tissue biopsies at diagnosis, during treatment and at progression. Serial acquisition of solid tumor biopsies during treatment to characterize mutations related to acquired resistance may not be medically feasible. Circulating tumor DNA (ctDNA) in plasma offers a possible noninvasive...

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PMID: 25858882
DOI: 10.1002/cpt.130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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