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Circulating Tumor DNA: Measurement and Clinical Utility

28 Aug 2017

Abstract excerpt

Circulating tumor DNA (ctDNA) is a component of the "naked" DNA found in blood. It can be isolated from plasma and represents combined genetic material from the primary tumor and metastases. Quantitative and qualitative information about a cancer, including mutations, can be derived using digital polymerase chain reaction and other technologies. This "liquid biopsy" is quicker and more easily repeated than tissue...

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PMID: 28846488
DOI: 10.1146/annurev-med-041316-085721

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