Article
Common variants of chemokine receptor gene CXCR3 and its ligands CXCL10 and CXCL11 associated with vascular permeability of dengue infection in peninsular Malaysia.
Human immunology - 1 Jun 2015
Hoh B P, Umi-Shakina H, Zuraihan Z, Zaiharina M Z, Rafidah-Hanim S, Mahiran M, Khairudin N Y Nik, Benedict L H Sim, Masliza Z, Christopher K C Lee, Sazaly A B
Abstract excerpt
Dengue causes significantly more human disease than any other arboviruses. It causes a spectrum of illness, ranging from mild self-limited fever, to severe and fatal dengue hemorrhagic fever, as evidenced by vascular leakage and multifactorial hemostatic abnormalities. There is no specific treatment available till date. Evidence shows that chemokines CXCL10, CXCL11 and their receptor CXCR3 are involved in...
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