Article
The roles of RgpB and Kgp in late onset gingipain activity in the vimA-defective mutant of Porphyromonas gingivalis W83.
Molecular oral microbiology - 1 Oct 2015
Dou Y, Robles A, Roy F, Aruni A W, Sandberg L, Nothnagel E, Fletcher H M
Abstract excerpt
Previous studies have shown that VimA, an acetyltransferase, can modulate gingipain biogenesis in Porphyromonas gingivalis. Inactivation of the vimA gene resulted in isogenic mutants that showed a late onset of gingipain activity that only occurred during the stationary growth phase. To further elucidate the role and contribution of the gingipains in this VimA-dependent process, isogenic mutants defective in the...
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