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[Generation and identification of P210(T315I-BCR/ABL) transgenic mice].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Mar 2015

Zhu Yufeng, Wang Yuanzhan, Meng Fanyi

Abstract excerpt

OBJECTIVE: To construct the P210(T315I-BCR/ABL) transgenic mice model. METHODS: The transgenic vector in which the P210(T315I-BCR/ABL) gene and eGFP gene was derived by APN/CD13 promoter was constructed and microinjected into the single-cell fertilized eggs of C57 mice. Transgene integration was conformed by PCR genotyping and P210(T315I-BCR/ABL) expression levels was evaluated by RT-PCR. The CML phenotype was...

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Share to Leukemia, Myelogenous, Chronic, BCR-ABL Positive

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Source

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Identifiers

PMID: 25854466
DOI: 10.3760/cma.j.issn.0253-2727.2015.03.010
PMCID: PMC7342520

Genes

BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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