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Article

NOD1 in contrast to NOD2 functional polymorphism influence Chlamydia trachomatis infection and the risk of tubal factor infertility.

Pathogens and disease - 1 Feb 2015

Branković Ivan, van Ess Eleanne F, Noz Marlies P, Wiericx Wilhelmina Anke J, Spaargaren Joke, Morré Servaas A, Ouburg Sander

Abstract excerpt

Intracellular pattern-recognition receptors NOD1 and NOD2 are capable of sensing common structural units of bacterial walls. Recognition triggers specific immune signalling pathways and leads to pro-inflammatory cytokine upregulation and adequate immune response. We investigated whether two functional polymorphisms in NOD1 and NOD2 exert an effect on susceptibility to (STD patients) and severity of (female...

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Source

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Identifiers

PMID: 25854006
DOI: 10.1093/femspd/ftu028
PMCID: PMC4542905

Genes

NOD1
NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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