Article
Role of the capsular polysaccharide as a virulence factor for Streptococcus suis serotype 14.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire - 1 Apr 2015
Roy David, Auger Jean-Philippe, Segura Mariela, Fittipaldi Nahuel, Takamatsu Daisuke, Okura Masatoshi, Gottschalk Marcelo
Abstract excerpt
Streptococcus suis is an important swine pathogen and a zoonotic agent causing meningitis and septicemia. Although serotype 2 is the most virulent type, serotype 14 is emerging, and understanding of its pathogenesis is limited. To study the role of the capsular polysaccharide (CPS) of serotype 14 as a virulence factor, we constructed knockout mutants devoid of either cps14B, a highly conserved regulatory gene, or...
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