Article
Screening for phagocytosis resistance-related genes via a transposon mutant library of Streptococcus suis serotype 2.
Virulence - 1 Dec 2020
Pei Xiaomeng, Liu Mingxing, Zhou Hong, Fan Hongjie
Abstract excerpt
STREPTOCOCCUS SUIS: serotype 2 (SS2) is a serious zoonotic pathogen which causes symptoms of streptococcal toxic shock syndrome (STSS) and septicemia; these symptoms suggest that SS2 may have evade innate immunity. Phagocytosis is an important innate immunity process where phagocytosed pathogens are killed by lysosome enzymes, reactive oxygen, and nitrogen species, and acidic environments in macrophages following...
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